北京索萊寶科技
專注于生物學試劑及試劑盒領域
服務熱線：18101056239
專注于生物學試劑及試劑盒領域
服務熱線：18101056239
產品型號：K106477P
更新時間：2022-08-15
廠商性質：生產廠家
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產品分類
Anti-XBP1 Polyclonal Antibody
| 英文名稱 | Anti-XBP1 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 別名 | TREB-5;XBP2;TREB5;XBP-1; |
| 應用 | WB |
| 稀釋比例 | WB 1:3000. |
| 交叉反應 | Human Mouse Rat |
| 蛋白分子量 | 45kDa |
| Gene ID | 7494 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 儲存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 純化方法 | Affinity purification |
| 亞型 | IgG |
| 免疫原 | A synthetic peptide of human XBP1 |
| 性狀 | 液體 |
| Public Immunogen Range | A synthetic peptide of human XBP1 |
| Subcellular Locations | Nucleus |
| Swiss Prot | P17861 |
| 克隆類型 | Polyclonal Antibody |
| 背景資料 | This gene encodes a transcription factor that regulates MHC class II genes by binding to a promoter element referred to as an X box. This gene product is a bZIP protein, which was also identified as a cellular transcription factor that binds to an enhancer in the promoter of the T cell leukemia virus type 1 promoter. It may increase expression of viral proteins by acting as the DNA binding partner of a viral transactivator. It has been found that upon accumulation of unfolded proteins in the endoplasmic reticulum (ER), the mRNA of this gene is processed to an active form by an unconventional splicing mechanism that is mediated by the endonuclease inositol-requiring enzyme 1 (IRE1). |
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